Novel Small Molecule Targeting Huntington’s Disease Is Ready for Clinical Trials

From sailing to the remote islands of French Polynesia and exploring Japan’s ancient Zen traditions to riding a historic steam train through Colorado’s Wild West, some adventures are simply too good to miss, whatever your age. For travellers in their 50s, 60s, 70s and beyond, 2027 offers plenty of opportunities to discover somewhere new, revisit places that hold special memories or finally embark on a long-dreamed-of journey. Whether it’s retracing the footsteps of Elvis Presley in Memphis 50 years after his death, discovering the wild landscapes of Florida’s Everglades or taking the scenic route to the French Alps aboard a sleeper train, these 12 unforgettable holidays prove that a sense of adventure never gets old.

Global tourism is entering a new era of strategic choices. The industry is still generating economic growth, but geopolitical instability, climate pressures, investment challenges and technological disruption are testing its long-term competitiveness. The numbers reveal a paradox. According to the World Economic Forum’s Travel & Tourism Development Index 2026, 92% of the 110 economies assessed have improved their conditions for tourism development since 2024. The World Travel & Tourism Council (WTTC) forecasts a US$12 trillion contribution to the global economy in 2026, supporting around 376 million jobs.

“I think about quitting all the time,” says Jordan Leung, known to his Instagram followers as @69ranch. As one of Hong Kong’s most prominent stand-up comedians to emerge in recent years, Leung’s pessimism is surprising. “I don’t wanna make social media content,” the 33-year-old admits. “Now I’m just fixated on likes and stuff … I don’t know how much longer I can do this.” Sitting directly across the table from him, it is not always easy to tell when Leung is being sincere or performing his...

There's no need to panic in a random gas station without TP when these handy portable wipes exist. View Entire Post ›

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For a while, the blueprint for a serious wellness trip looked pretty much the same everywhere. A flight to somewhere warm, a resort with a view of jungle or terraced rice paddies, a treatment menu borrowing names from ancient traditions, and enough linen to last a lifetime. Scotland was never really part of that picture. It was the place people went for whisky, castles and rain, not the place they went to reset. Then this summer, Scotland’s men’s football team appeared at their first World Cup...

If you feel lost or overwhelmed now your children have left the nest, you are far from alone. Many parents experience empty nest syndrome at this time of the year. “Empty nest syndrome isn’t a mental health condition, but a set of feelings or symptoms that parents might feel when all their children have left home,” says Dr Elizabeth Wakeland, consultant, clinical and forensic psychologist at Cygnet Health Care in the UK. “It’s a period of significant life change where parents are trying to...

A powerful, brief downpour sent Disneyland visitors scrambling for cover Friday night, closed rides and flooded parts of Frontierland as workers tried to clear backed-up drains.

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With Clayface, DC trades its usual cape-donning heroes for a chilling entry into body-horror cinema. Starring Tom Rhys Harries, the film follows Matt Hagen (played by Harries), a Hollywood star from Gotham whose run-in with a crime boss leaves his face severely disfigured. Desperate to restore himself, Hagen turns to Dr. Caitlyn Corr (Naomi Ackie), whose experimental treatment makes matters worse. So Hagen finds himself on a path from Hollywood’s charming leading man to a Gotham City...

The historic Mt. Waterman Ski Resort, one of Southern California's steepest ski resorts and only an hour from downtown Los Angeles, was relisted for sale on Wednesday at $3,275,000.

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